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Repeat Expansion Disorders CRISPR-Cas systems Nuclear RNA Biology SARS-CoV-2, HIV-1, HBV |
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Repeat Expansion RNA RNA-Guided Enzymes Long Noncoding RNA RNA virus 'omics |
Lab News07-01-2023
The Gagnon laboratory officially moved to the Department of Biochemistry in the Wake Forest University School of Medicine. 05-06-2023 Our paper on rapid Mpox genome sequencing with nanopore and lineage tracing was published in Virology Journal! Congratulations to Dr. Mike Bosmeny on this first author paper. 04-12-2023 Our paper on Cas12a RNP assembly dynamics, in collaboration with the Pradeepkumar, Damha, and Moran labs, was published in JBC! 03-08-2022 Dr. Gagnon is officially promoted to full Professor beginning July 1, 2023! 12-12-2022 Welcome new graduate students to the Gagnon laboratory: Emmanuel Sasu, Lydia Larkai, and Zafeiria Nikolaidi! 07-21-2022 Abadat Yinusa successfully defended her MS thesis. Congratulations Abadat! Good luck at your new industry position. 06-30-2022 Katy Ovington successfully defended her PhD thesis. Congratulations Dr. Ovington! Good luck at your new postdoc position. 06-20-2022 Rama's paper on how to clone and validate problematic GC-rich and repetitive shRNAs has been accepted in Human Gene Therapy. 04-28-2022 The Gagnon laboratory, in collaboration with the Joao Mamede laboratory (Rush University) has been awarded an NIH R61 from NIAID to study the epitranscriptomics of HIV in patients taking cART and to identify potential therapeutic approaches to address persistent infection. 01-03-2022 Dr. Michael Bosmeny and Dr. Christopher Barkau join the Gagnon laboratory as postdocs. 12-17-2021 Christopher Barkau successfully defended his PhD thesis. Congratulations Dr. Chris! 12-15-2021 New graduate students Solomon Punobyin, Ashmita Dhakal, Patrick Brown, and Jacob Marrs join the Gagnon laboratory. Welcome! 11-15-2021 Eman and Ramadevi, in collaboration with the Masad Damha laboratory, publish their paper on Cas12a guide RNA chemical modification in Nature Communications. 09-27-2021 Adrian and the SARS-CoV-2 sequencing team's method paper on how to sequence COVID-19 clinical samples in high throughput is published in JBM. 02-27-2021 Chris' review on anti-CRISPR technologies close to the clinic is published in Biochemical Pharmacology. 01-10-2021 The Gagnon lab identifies a new SARS-CoV-2 variant that is dominant in, and specific to, the U.S. 12-16-2021 Zach's paper using the Broccoli RNA aptamer as a readout for polymerase activity optimization is published in JBC. 12-15-2020 New graduate students Paige Metz and Adam White join the Gagnon laboratory. Welcome! 10-01-2020 The Gagnon lab is awarded a grant to work with the Chicago CAN Initiative and the Walder Foundation to sequence SARS-CoV-2 genomes and track the emergence of new variants in Chicago and greater Illinois. 10-01-2020 Fatima El Azzouzi joins our group as a Researcher III technician. Welcome Fatima! 09-01-2020 Rourke Sylvain joins our group as a Researcher I technician. Welcome Rourke! 04-01-2020 Kushal Rohilla successfully defended her PhD thesis work. Congratulations Dr. Kushal! Good luck in your new industry position. 02-28-2020 Eman is awarded the one-year IBK-MIT fellowship to study at the Massachusetts Institute of Technology (MIT) beginning in September 2020! Good luck in your new postdoc position. 02-14-2020 Keith was informed that the Dean has approved his tenure with promotion to Associate Professor. 01-16-2020 Our anti-CRISPR nucleic acids are cited in a news article in Nature covering anti-CRISPR technology and gene editing. 01-13-2020 The Gagnon laboratory is awarded an R21 to investigate the potential repurposing of a class of small molecules as inhibitors of C9ORF72 repeat expansion transcription. 01-03-2020 Keith is awarded an R01 to characterize and develop anti-CRISPR nucleic acids. 12-17-2019 Eman Ageely successfully defended her PhD thesis work! Congratulations Eman! 12-15-2019 Graduate students Seth Eddington and Abadat Yinusa join the Gagnon laboratory. Welcome 12-14-2019 Courtney Slavich finished with her Masters and graduated. Good luck on your next adventure Courtney! 10-19-2019 The Gagnon lab and Gupta lab travel together to Mizzou to participate in the RNA Cornbelt Meeting. 10-15-2019 Chris gave a talk on his anti-CRISPR work at the OTS meeting in Munich! 6-10-2019 The New England Journal of Medicine published a commentary by Steven Dowdy covering our recent nucleic acid-based anti-CRISPR research! 6-10-2019 Keith is notified that his NIH R03 proposal was selected for funding. 4-19-2019 Kushal Rohilla is awarded an SIU Dissertation Research Award (DRA). 4-16-2019 Chris Barkau's paper on novel anti-CRISPR small nucleic acid-based inhibitors (CRISPR SNuBs) is accepted for publication in Nucleic Acid Therapeutics and highlighted on the cover with Chris' custom cover art. 3-23-2019 Keith and Dr. David Corey published guidelines for experiments with antisense oligos and small RNAs in Nucleic Acid Therapeutics. 3-10-2019 Keith is notified that his NIH R15 proposal was selected for funding. 12-18-2018 Keith is elected to a two-year term on the Oligonucleotide Therapeutics Society (OTS) Board of Directors. 12-15-2018 Zachary Kartje graduated with his PhD and accepted a postdoc position with Jon Watts at the RNA Therapeutics Institute at the UMass Medical Center. Congratulations! 12-13-2018 Mansi Parasrampuria joins the Gagnon lab to pursue a PhD through the Microbiology, Biochemistry and Molecular Biology graduate program. Welcome! 12-06-2018 Adrian Pater joins the Gagnon lab to pursue a PhD through the Chemistry and Biochemistry graduate program. Welcome! 12-05-2018 The Gagnon lab published a study with the Masad Damha lab on extensively chemically-modified CRISPR RNA in Nucleic Acids Research. 5-10-2018 The Gagnon lab published a study on RNA-DNA chimeric CRISPR-Cas9 in Biochemistry. 4-28-2018 Zach Kartje is awarded an SIU Dissertation Research Award (DRA). 4-25-2018 Zach Kartje wins first place for his oral presentation at the SIU School of Medicine Gradaute Research Symposium held in Springfield, Illinois. 4-15-2018 Kushal Rohilla wins an SIU Graduate and Professional Graduate Research (GPSC) Award. 3-15-2018 Courtney Slavich is awarded a 1 year fellowship through the SIU Graduate School. 2-22-2018 Undergraduate assistant and REACH Scholar Helen Mihm's research project on anti-venom aptamers is highlighted in local SIU news. 1-15-2018 The Gagnon lab is awarded a small internal SIU SOM grant to characterize RNA on the chromatin with a new sequencing technique. 12-11-2017 Graduate students Katy Ovington, Ramadevi Chilamkurthy, and Courtney Slavich join the Gagnon lab. Welcome! 10-03-2017 Guide BioSci, Inc. is announced as runner up for the IDT Synthetic Biology challenge at the SynBioBeta meeting in San Francisco. 08-29-2017 Congratulations to Kushal on publishing her review on RNA biology in repeat expansion disorders. 08-15-2017 Keith starts Guide BioSci, Inc., a precision CRISPR engineering company for biotech and therapeutic applications. 08-15-2017 Keith is awarded the OTS Young Investigator Award for 2017. 04-21-2017 Kushal Rohilla wins first place for her poster presentation at the 27th Annual SIU School of Medicine Graduate Research Symposium! 02-23-2017 Dr. Maria Barton joined the Gagnon lab as a postdoc. Welcome Maria! 11-28-2016 The Gagnon lab has been awarded an ALS research grant from the Judith and Jean Pape Adams Charitable Foundation to explore transcription and splicing of C9ORF72 as a potential therapeutic target for C9FTD/ALS. 11-11-2016 Keith and Kushal attended the 4th RNA Metabolism in Neurological Disease meeting in San Diego where Kushal presented a poster. 09-28-2016 Keith and Zach attended the 12th OTS meeting in Montreal. Congratulations to Zach for winning a poster award! 07-26-2016 Congratulations to Eman, Zach, Kushal and Chris for acceptance of their paper on the Broccoli RNA aptamer to ACS Chemical Biology! 06-24-2016 Eman Ageely successfully defended her M.S. thesis in Chemistry and Biochemistry. Congratulations! 05-10-2016 Undergraduate assistants Gisela Cairo-Baza and Ariadna Cairo-Baza leave for graduate school, Indiana University and UC Merced, respectively, to pursue their Ph.D. degrees. 02-15-2016 The Gagnon lab and Corey lab have published a crystal structure of the C9ORF72 antisense repeat RNA in Biochemistry. 01-06-2016 The Gagnon lab has been awarded an ALSRP Therapeutic Idea Award through the DoD for developing c9FTD/ALS model cell lines to search for potential ALS small molecule therapeutics. 10-15-2015 Keith attended the 11th OTS meeting in Leiden, The Netherlands and the 3rd RNA Metabolism in Neurological Disease meeting in Chicago, accompanied by Kushal, Zach and Eman. 08-16-2015 Welcome to graduate students Chris Barkay and Aiysha Althobaiti, who officially joined the Gagnon lab. 06-28-2015 The Gagnon lab has been awarded an ALS Association starter grant to develop and validate cell-based models of c9FTD/ALS. 05-31-2015 Attended the 20th Annual RNA Society Meeting in Madison, Wisconsin. Kushal, Zach and Eman all presented posters on their research progress. 04-24-2015 Undergraduates Gisela and Tony are awarded scholarships for 2015-2016 through the SIU Chemistry Department. 04-22-2015 Congratulations to Gisela and Ariadna for winning the competitive 2015-2016 REACH Award for their team project proposal. 12-19-2014 The Gagnon lab has been awarded a seed grant through the SIU School of Medicine for team development grant (TDG) proposal, in collaboration with Sean Moran's lab at SIU, to study the aggregation of repeat expansion RNA and dipeptides associated with c9FTD/ALS. 12-15-2014 Official demo begins in Neckers 208 to prepare our newly renovated laboratory. 11-8-2014 Finally got our Cary 400 (that we bought for a steal on Ebay) running... time to get some melt data!! 10-30-2014 Graduate student Kushal Rohilla joins the Gagnon lab. Welcome! 10-16-2014 Submitted our first NIH grant, an R03 for probing and detection of repeat expansion RNAs. 10-13-2014 Submitted a Team Development Grant (TDG) proposal to the SIU School of Medicine. 10-12-2014 Presented our first original work on detection of repeat expansion sequences at OTS 2014. 08-16-2014 Graduate students Eman Ageely and Zachary Kartje join the Gagnon lab. Welcome! 07-28-2014 Keith T. Gagnon begins his independent career as an assistant professor at SIU. |
Other TopicsAVAILABLE POSITIONS
Interested students or prospective postdocs are encouraged to inquire about positions. |
